프리컨퍼런스 워크샵 - 일본 시간(GMT+09:00)
등록
오전 접수
오전 워크샵 : 항체 엔지니어링 입문
워크샵 A : 항체 엔지니어링 입문
Today’s wealth of knowledge of antibody structures will be reviewed along with the genetics of diversity generation, to give insights into the best strategies for improving function. There is particular emphasis on the choice of a functional assay to effectively monitor the changes in a desired property, and the use of functional enrichment steps where a library approach is employed. Not only is amino acid sequence amenable to engineering, but glycan structures and other modifications may also be engineered. The course will focus on the engineering and enhancement of antibodies and antibody-like scaffolds. Examples will include work on antibody fragment affinity improvement by 100-fold to low pM affinity. Also, the engineering of bispecific antibodies by diverse approaches and the adaptation to generate Chimeric Antibody Receptor (CAR) constructs will be discussed. Expression platforms for producing antibodies for testing and for manufacture will also be covered. A background in biochemistry and molecular biology is useful, as the course is designed to progress rapidly from simple to advanced concepts.
- David Bramhill, PhD - Consultant, Bramhill Biological Consulting, LLC, USA
점심식사
휴식
점심식사 휴식·네트워킹
오후 워크샵 : ADC·컨쥬게이트 의약 입문
워크샵 B : ADC·컨쥬게이트 의약 입문
- David Bramhill, PhD - Consultant, Bramhill Biological Consulting, LLC, USA
휴식
프리컨퍼런스 워크샵 종료
* 주최측 사정에 따라 사전 예고없이 프로그램이 변경될 수 있습니다.
