2026년 디너 쇼트코스* (대면만)
*주최측 사정에 따라 사전 예고없이 프로그램이 변경될 수 있습니다.
Drug Discovery Chemistry의 쇼트코스는 교육적 및 상호 작용적이며, 특정 토픽에 관한 상세 정보를 Q&A 기회와 함께 제공하고 있습니다. 이 코스에서는 이 분야를 처음으로 접하는 사람이나 더 많이 배우고 싶은 사람을 위한 입문편을 포함하며, 메인 컨퍼런스 프레젠테이션에서는 시간이 허락하는 한, 많은 기술적 측면에 대해 설명하고 있습니다. 강사는 업계 및 학계로부터 섭외하며, 해당 분야의 권위자나 지도 경험자가 대부분입니다.
디너 쇼트코스는 4월 13일(월) 밤과 4월 15일(수) 밤에 개최되며, 대면 참가자를 대상으로 합니다.
Monday, April 13, 2026 6:00 - 8:30 pm
SC1: Protein Degraders: A Beyond Rule of Five Space and in vitro ADME Perspective
Instructors:
John Erve, PhD, President, Jerve Scientific Consulting
Stefanus Steyn, PhD, Research Fellow, Pharmacokinetics Dynamics & Metabolism, Pfizer
Topics to be Covered:
- Comparison of Rule of 5 and Beyond Rule of 5 space
- Importance of intramolecular hydrogen bonds for solubility and permeability
- Determining chameleonicity and its importance for PROTACs
- In vitro-assays to measure key ADME-features of degraders
- Pitfalls and points to consider when assessing degrader's ADME-features
- Linking in vitro- to in vivo-findings in terms of PK and PD
Who Should Attend:
INSTRUCTOR BIOGRAPHIES:
John Erve, PhD, President, Jerve Scientific Consulting
Stefanus Steyn, PhD, Research Fellow, Pharmacokinetics Dynamics & Metabolism, Pfizer
SC2: Fragment-Based Drug Design: Advancing Tools and Technologies
Instructors:
Daniel A. Erlanson, PhD, Chief Innovation Officer, Frontier Medicines Corporation
Ben J. Davis, PhD, Research Fellow, Biology, Vernalis R&D Ltd.
Topics to be Covered:
- Pros and cons of fragment-based approaches
- What makes a good fragment; properties of a good fragment library
- Finding, validating, and characterizing low-affinity ligands
- The importance of using orthogonal screening methods
- What to do with a fragment-growing, linking, and more
INSTRUCTOR BIOGRAPHIES:
Daniel A. Erlanson, PhD, Chief Innovation Officer, Frontier Medicines Corporation
Ben J. Davis, PhD, Research Fellow, Biology, Vernalis R&D Ltd.
SC3: Next-Gen AI Toolkit for Drug Discovery: From LLMs to Multi-Agent Systems
Instructors:
Parthiban Srinivasan, PhD, Professor and Director, Centre for AI in Medicine, Vinayaka Mission's Research Foundation, India
Petrina Kamya, PhD, Global Head of AI Platforms & Vice President, Insilico Medicine; President, Insilico Medicine Canada
Topics to be Covered:
- A clear understanding of how drug discovery is shifting from LLM-based tools to multi-agent AI ecosystems
- Insights into the role of foundation models, Sci-LLMs, and agentic frameworks in accelerating pharmaceutical innovation
- Access to curated links, references, and resources for further exploration and practical application beyond the course
Who Should Attend:
INSTRUCTOR BIOGRAPHIES:
Parthiban Srinivasan, PhD, Professor and Director, Centre for AI in Medicine, Vinayaka Mission's Research Foundation, India
Petrina Kamya, PhD, Global Head of AI Platforms & Vice President, Insilico Medicine; President, Insilico Medicine Canada
SC4: From Biophysics to Cellular Target Engagement: Tools for Small Molecule Ligand Identification & Analysis
Instructors:
Hans-Peter N. Biemann, PhD, Distinguished Scientist, Integrated Drug Discovery, Sanofi
Karanbir Pahil, PhD, Senior Principal Scientist, Affinity Selections & Biophysics, GlaxoSmithKline
Matthew T. Eddy, PhD, Assistant Professor, Chemistry, University of Florida, Gainesville
Elmar Nurmemmedov, PhD, MBA, Co-Founder & CEO, CellarisBio
Topics to be Covered:
- Affinity Selection Mass Spectrometry (ASMS): Overview, Outsourcing --Hans Biemann, Sanofi\
- Applying Orthogonal Biophysical Tools to Hit Discovery & Follow-Up: SPR, Mass Spectrometry, ASMS, Thermal Shift assays - Karanbir Pahil, GSK
- Biophysical Approaches for GPCRs: NMR, CryoEM advances, Nanodiscs -- Matthew Eddy, University of Florida
- Fluorescence Resonance Energy Transfer (FRET) & Cellular Target Engagement -- Elmar Nurmemmedov, CellarisBio
INSTRUCTOR BIOGRAPHIES:
Hans-Peter N. Biemann, PhD, Distinguished Scientist, Integrated Drug Discovery, Sanofi
Karanbir Pahil, PhD, Senior Principal Scientist, Affinity Selections & Biophysics, GlaxoSmithKline
Matthew T. Eddy, PhD, Assistant Professor, Chemistry, University of Florida, Gainesville
Wednesday, April 15, 2026 6:15 - 8:45 pm
SC5: Protein Degraders: An in vivo ADME and Safety Perspective
Instructors:
Prasoon Chaturvedi, PhD, Vice President & Head, DMPK, C4 Therapeutics, Inc.
John Erve, PhD, President, Jerve Scientific Consulting
Topics to be Covered:
- In vivo ADME properties of PROTACs
- Delivery of PROTACs
- PROTAC PK-PD correlation
- Safety issues unique to PROTACs
- Circadian rhythm considerations
Who Should Attend:
Scientists in the field of proteolysis targeting chimeras (PROTACs) and would like to deepen their understanding of these molecules and the physicochemical attributes that may contribute to their success as oral drugs. ADME scientists and medicinal chemists wishing to understand PROTACs from a drug safety and metabolism perspective. Graduate students and academic scientists interested in learning more about this rapidly developing new drug modality.
INSTRUCTOR BIOGRAPHIES:
Prasoon Chaturvedi, PhD, Vice President & Head, DMPK, C4 Therapeutics, Inc.
John Erve, PhD, President, Jerve Scientific Consulting
SC6: Chemical Biology for Covalent Drug Discovery, Phenotypic Screening, and Target Deconvolution
Instructors:
Paul Brennan, PhD, Professor, Nuffield Department of Medicine, University of Oxford
Jarrett Remsberg, PhD, Senior Scientist, Discovery Technologies, Belharra Therapeutics
Angelo Andres, Senior Scientist, Chemical Biology, AstraZeneca
Topics to be Covered:
- Chemical biology assays and probes for target engagement, deconvolution, and mechanistic understanding
- Chemoproteomic methods and reagents for covalent ligand drug discovery
- Comparison of various chemical biology approaches (mass spectrometry, affinity-bead methods, thermal profiling, and more)
- Use of quantitative mass spectrometry-based proteomics and global proteomics
- Cysteine profiling and covalent inhibitors for target discovery and occupancy
- Design and screening of chemogenomics libraries for target identification
- Case studies highlighting use of proteomics for target engagement and deconvolution
- Proximity proteomics for discovering novel targets and assessing druggable hypothesis
INSTRUCTOR BIOGRAPHIES:
Paul Brennan, PhD, Professor, Nuffield Department of Medicine, University of Oxford
Jarrett Remsberg, PhD, Senior Scientist, Discovery Technologies, Belharra Therapeutics
Angelo Andres, Senior Scientist, Chemical Biology, AstraZeneca
SC7: DNA-Encoded Libraries in Drug Discovery: Design, Screening, and Lead Development
Instructors:
Svetlana Belyanskaya, PhD, Co-Founder, DEL Source; Former DEL Platform Manager; GSK; Vice President, Biology, Anagenex
Ghotas Evindar, PhD, Co-Founder & President, DEL Source; Former DEL Platform Senior Manager, GSK; and Head of Research at Exo Therapeutics and 1859
Ching-Hsuan Tsai, PhD, Executive Director, Structure Therapeutics
Topics to be Covered:
- DEL Overview: Principles, advantages, and drug discovery applications
- Design & Synthesis: DNA coding, library architecture, and chemistry advances
- Screening Strategies: Affinity-based DEL selections, solution-phase, and OBOC
- DELs Applications & Trends: Advances in cell-based and GPCR screening
- Data & Validation: Analysis pipelines, hit confirmation, and AIML applications
INSTRUCTOR BIOGRAPHIES:
Svetlana Belyanskaya, PhD, Co-Founder, DEL Source; Former DEL Platform Manager; GSK; Vice President, Biology, Anagenex
Ghotas Evindar, PhD, Co-Founder & President, DEL Source; Former DEL Platform Senior Manager, GSK; and Head of Research at Exo Therapeutics and 1859
Ching-Hsuan Tsai, PhD, Executive Director, Structure Therapeutics
*주최측 사정에 따라 사전 예고없이 프로그램이 변경될 수 있습니다.


























