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Solid Tumors 2025: Technologies, Diagnostics & Therapeutics

Solid Tumors 2025: Technologies, Diagnostics & Therapeutics
ÀÏÁ¤ : 2025³â 11¿ù 20-21ÀÏ
°³ÃÖ: Laguna Hills, California, USA
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Charles Keller, Scientific Director, Children¡¯s Cancer Therapy Development Institute

Hervé Tiriac

Hervé Tiriac, Researcher, University of California-San Diego

Michael Graner

Michael Graner, Professor, University of Colorado Anschutz Medical Campus


Roger Royse, Partner, Haynes & Boone, LLP -- Conference Chairperson

Solid Tumors 2025: Technologies, Diagnostics & Therapeutics

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  • Progress in Research Trends Targeting Various Classes of Solid Tumors
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Charles Keller, Scientific Director, Children¡¯s Cancer Therapy Development Institute
Charles Keller
Charles Keller Biographical Sketch

Charles¡¯ research focuses on the development of more effective, less toxic therapies for childhood cancers. His special interest is advanced disease that has spread beyond the initial location of the cancer or which makes the tumor unresectable. Charles has co-chaired the brain tumor developmental therapeutics committee (CNS-DVL) of the Children¡¯s Oncology Group and is a member of the soft tissue sarcoma (STS) committee of Children¡¯s Oncology Group. He has also regularly been a standing or ad hoc member of NIH/NCI Study Sections.

Charles attended Tulane University where he received a degree in Biomedical Engineering prior to attending Baylor College of Medicine where he received his M.D. degree. After completing his internship and residency in Pediatrics at Texas Children¡¯s Hospital, Charles trained in Pediatric Hematology-Oncology at the University of Utah and with 2007 Nobel laureate, Mario Capecchi. Charles has authored over 150 scientific publications and is a recognized expert in the biology of childhood sarcomas and the preclinical investigation of childhood cancers. Charles is also a co-founder of Artisan Biopharma (a company helping translate drug discoveries to clinical use) and Tio Companies that improves drug safety and cancer drug effectiveness*.

* overlap between cc-TDI, Artisan Biopharma, Teo Therapeutics and Tio Companies is overseen by a conflict of interest management committee.


Hervé Tiriac, Researcher, University of California-San Diego
Hervé Tiriac
Hervé Tiriac Biographical Sketch

Dr. Tiriac received his Ph.D. from UC San Diego studying pre-mRNA splicing and transcription with Dr. Tracy Johnson. Herve¡¯s research focuses on developing systems for precision medicine that may be utilized in the fight against pancreatic cancer. Herve did his postdoctoral fellowship with David Tuveson at Cold Spring Harbor Laboratory where he collaborated with Hans Clevers to establish protocols for PDAC organoid generation and testing.


Michael Graner, Professor, University of Colorado Anschutz Medical Campus
Michael Graner
Michael Graner Biographical Sketch

Michael Graner received his PhD in Biochemistry from the University of Illinois followed by post-doctoral and research faculty work at the University of Arizona, shifting gears from the Drosophila extracellular matrix to cancer immunotherapy. He then took at faculty position at Duke University¡¯s Tisch Brain Tumor Center, followed by his current position as Professor in Neurosurgery at the University of Colorado Denver (Anschutz Medical Campus). He is also a member of the University of Colorado Cancer Center, the Colorado Clinical and Translational Sciences Institute, the MAVRC Program, and holds a Visiting Professorship Appointment at the Shenzhen Third People¡¯s Hospital (China) and an adjunct faculty appointment at Colorado State University. Graner has a long-standing interest in cell stress responses, which led to cancer vaccine development (including one in clinical trials), which somehow led to the world of extracellular vesicles (EVs). His lab currently concentrates on signaling mechanisms involving EVs, in particular the transfer of stressed phenotypes from stressed tumor cells to unstressed ones via EVs.


Roger Royse, Partner, Haynes & Boone, LLP
Roger Royse
Roger Royse Biographical Sketch

Roger Royse is a startup lawyer in Silicon Valley and a pancreatic cancer patient. Roger was diagnosed with stage 2B pancreatic adenocarcinoma in July 2022 after taking a multi cancer early detection blood test. After 6 months of chemotherapy and surgery and an experimental cancer vaccine, Roger currently has no evidence of disease.

Roger has been active for many years with the Leukemia Lymphoma Society having been its Bay area Man of the Year in 2012. Since his diagnosis, Roger has become the Silicon valley Advocacy Chair for the Pancreatic Cancer Action Network (PanCan) and has joined the board of the Cancer Patient Lab.org, a nonprofit dedicated to evidence based therapies. Roger also hosts www.cancerstartup.com, a platform for cancer therapy technology startups to demo their solutions. Roger has since testified to an FDA Advisory committee on multi cancer early detection and has been featured in many publications including the Wall Street Journal on MCED.

Roger believes in the patient being proactive and taking personal responsibility for their health and being very involved in their treatment decisions based on evidence based treatments.


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  • Progress in Research Trends Targeting Various Classes of Solid Tumors
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20 November 2025

08:00

Conference Registration: Garnet Gallery

Conference Registration, Materials Pick-Up, Coffee and Continental Breakfast


20 November 2025

09:00

Garnet Gallery, VOCO Hotel

Roger Royse HAYNES BOONE

Roger Royse, Partner, Haynes & Boone, LLP -- Conference Chairperson

Patient Driven Oncology

A summary of the patient¡¯s perspective on cancer care.


20 November 2025

09:29

Garnet Gallery, VOCO Hotel

Session Title: Research Strides in Understanding of Various Cancer Classes -- Presentations on Mechanisms of Oncogenic Development, Molecular Switches, and Signal Transduction


20 November 2025

09:30

Garnet Gallery, VOCO Hotel

Charles Keller

Charles Keller, Scientific Director, Children¡¯s Cancer Therapy Development Institute, United States of America

Inhibition of Oncogenic Fusion Proteins in Pediatric Solid Tumors

Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood and often also occurs in adolescents and young adults. Clinically, survival amongst metastatic RMS patients has remained dismal and unimproved for decades. Metastatic RMS harboring PAX3/7::FOXO1 is generally not survivable. RMS has two major forms: the alveolar subtype (ARMS or Fusion+ RMS) is characterized in 66% of cases by a t(2;13) translocation creating an oncogenic PAX3::FOXO1 chimeric transcription factor. Approaches that have brought repurposed targeted therapeutics to clinical trials, approaches to create bespoke inhibitors and degraders, and technologies that enable pharma to quickly and economically empower pharma to develop de novo therapeutics for rare solid tumors will be presented.


20 November 2025

10:00

Garnet Gallery, VOCO Hotel

Michael Graner

Michael Graner, Professor, University of Colorado Anschutz Medical Campus, United States of America

Title to be Confirmed


20 November 2025

10:30

Garnet Gallery, VOCO Hotel

Mid-Morning Coffee Break and Networking


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Solid Tumors 2025: Technologies, Diagnostics & Therapeutics Conference °³ÃÖÁö

SelectBIO is pleased to host this Solid Tumors 2025: Technologies, Diagnostics & Therapeutics Conference at VOCO Laguna Hills: An IHG Hotel -- Laguna Hills, California.

VOCO Laguna Hills
25205 La Paz Road
Laguna Hills, California 92653, USA

This hotel in Southern California is easily accessible from Los Angeles and San Diego via Interstate-5 (I-5).

  • The nearest airport is: John Wayne Airport (SNA) - 13.7 miles from the hotel.
  • From Los Angeles International Airport (LAX) - the hotel is 52.9 miles.
  • The hotel is within a short drive of Disneyland and Legoland California, as well as Laguna Beach, Newport Beach, as well as shopping and dining at South Coast Plaza in Costa Mesa.
  • All conference sessions, exhibition as well as networking reception will be held in the Conference Center at VOCO Laguna Hills.
SelectBIO has negotiated discounted hotel room pricing for conference attendees at VOCO Laguna Hills.

To make your Hotel Reservations Online: Click the Button Below to Open the Hotel Booking Website This will provide a SelectBIO discounted rate for booking hotel rooms.

VOCO Laguna Hills VOCO Laguna Hills VOCO Laguna Hills VOCO Laguna Hills

For any hotel reservation-related issues, or if you need any help with hotel bookings, please contact us.

SelectBIO has NOT authorized ANY third party company to assist in hotel bookings or reservations for the conference. Please do NOT do business with any third party companies. If in doubt, please contact us immediately to clarify.