쇼트코스

2018년 11월 27일|18:00-20:30

쇼트코스 1:Drug Discovery 연구자를 위한 면역학 기초 강좌, 파트 1:면역계 개요

This short course provides an introduction to human immunology for discovery pharmacologists, biologists and chemists working in the biopharmaceutical industry. It will review how the immune system is organized and gives rise to both normal and pathogenic immune responses. Topics will include pathogen recognition by innate immune cells, antigen generation and presentation to lymphocytes, effector mechanisms of T cells, antibody generation and the molecular basis of pathogenic immune responses.

Instructor:

Thomas Sundberg, PhD, Senior Research Scientist I, Center for Development of Therapeutics, Broad Institute of MIT and Harvard

쇼트코스 2:약물 대사와 약물 운송의 주요 개념

This short course will focus on basic aspects of drug metabolism and drug transporters and their impact in drug research and development. The drug metabolism section will briefly cover the historical basis of early drug metabolism studies, important biotransformations with relevant mechanistic details, some strategies that medicinal chemists use to influence drug metabolism and finally, the role of reactive metabolites in drug toxicity. The drug transporter section will cover conceptual aspects of experimental design, including set-up, pitfalls and data interpretation. The relevance of drug transport processes for key ADME and safety properties will be discussed and exemplified with different case studies. The audience will learn where and how drug transport properties can be optimized throughout lead-optimization to improve drug absorption and distribution, organ targeting and drug safety.

Instructors:

John C. L. Erve, PhD, DABT, Jerve Scientific Consulting, Inc.

Bruno Stieger, PhD, Department of Clinical Pharmacology and Toxicology, University Hospital Zurich

쇼트코스 3:장기 칩 시스템의 기점, 최적화, 응용

This short course will take a more in depth look at the origins, optimization and application of organ-on-a-chip systems. This course will cover the essential tools and techniques employed in the development and application of organ-on-a-chip and MicroPhysiological systems in more detail. Topics covered will include the integration of non-biological chips with modern cell culture, microfabrication techniques, 2D and 3D applications, increasing throughput and insuring quality control. Participants can expect to gain a greater understanding of the history and background of organ-on-a-chip devices, their current capabilities, current and future industrial applications.

Instructors:

James J. Hickman, PhD, Professor, NanoScience Technology Center, University of Central Florida

Peter Loskill, PhD, Assistant Professor for Experimental Regenerative Medicine, Department of Women’s Health, Research Institute for Women’s Health, Faculty of Medicine, Eberhard Karls University Tübingen

Wendy Rowan, PhD, FRSB, Associate GSK Fellow, Scientific Leader Target Sciences, GlaxoSmithKline

2018년 11월 29일|19:00-21:30

쇼트코스 4:Drug Discovery 연구자를 위한 면역학 기초 강좌, 파트 2:암면역과 자가면역

This short course will provide a brief overview of the organization of the immune system that will then serve as the basis for discussions of how the immune system can be modulated through biopharmaceutical intervention to either enhance anti-tumor immunity or suppress pathogenic inflammation. We will cover basic principles of immune-oncology (e.g., checkpoint blockade) and progress in targeting immune processes with small molecules and protein-based immunomodulatory therapies.

Instructor:

Thomas Sundberg, PhD, Senior Research Scientist I, Center for Development of Therapeutics, Broad Institute of MIT and Harvard

쇼트코스 5:인간화 마우스 모델:기 개요와 암 면역치료의 전임상 평가에 대한 응용

Humanized mouse models have been developed as immunologically relevant models for preclinical profiling of cancer immunotherapies. The course will describe different types of humanized mouse models, their immune characterization, and specific examples of their application in the field of cancer immunotherapy. The course will highlight advantages and pitfalls of currently available humanized mouse models and will give an overview of the next-generation improved humanized models designed to better address specific immunological questions.

Instructor:

Michael Brehm, PhD, Associate Professor, The Robert and Sandra Glass Term Chair in Diabetes, Diabetes Center of Excellence, Program in Molecular Medicine, University of Massachusetts Medical School

* 주최측 사정에 따라 사전 예고없이 프로그램이 변경될 수 있습니다.

Choose your language
Traditional Chinese
Simplified Chinese
Japanese
English



Catalog Download
Catalog




메일링 서비스
메일링 서비스